Design approaches to experimental mediation
نویسندگان
چکیده
منابع مشابه
Theoretical and experimental approaches to design effective antisense oligonucleotides.
Among the large number of possible antisense oligonucleotides (asODN) against a given target nucleic acid, only a small number of species seems to give rise to satisfactorily strong inhibition of target gene expression in living cells. Therefore much attention is paid to strategies that help to successfully design effective asODN. Here, selected experimental approaches and theoretical concepts ...
متن کاملFragment based drug design: from experimental to computational approaches.
Fragment based drug design has emerged as an effective alternative to high throughput screening for the identification of lead compounds in drug discovery in the past fifteen years. Fragment based screening and optimization methods have achieved credible success in many drug discovery projects with one approved drug and many more compounds in clinical trials. The fragment based drug design star...
متن کاملInvolving students in experimental design: three approaches.
Many faculty want to involve students more actively in laboratories and in experimental design. However, just "turning them loose in the lab" is time-consuming and can be frustrating for both students and faculty. We describe three different ways of providing structures for labs that require students to design their own experiments but guide the choices. One approach emphasizes invertebrate pre...
متن کاملClassical and causal inference approaches to statistical mediation analysis.
BACKGROUND Although there is a broad consensus on the use of statistical procedures for mediation analysis in psychological research, the interpretation of the effect of mediation is highly controversial because of the potential violation of the assumptions required in application, most of which are ignored in practice. METHOD This paper summarises two currently independent procedures for med...
متن کاملClassical and causal inference approaches to statistical mediation analysis
Resumen Background: Although there is a broad consensus on the use of statistical procedures for mediation analysis in psychological research, the interpretation of the effect of mediation is highly controversial because of the potential violation of the assumptions required in application, most of which are ignored in practice. Method: This paper summarises two currently independent procedures...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Experimental Social Psychology
سال: 2016
ISSN: 0022-1031
DOI: 10.1016/j.jesp.2015.09.012